This manual, specifically designed for the grain sector, integrates key principles for mycotoxin prevention and control, drawing on the foundational insights from Matumba et al. (2021) and comprehensive stakeholder consultations. It aims to provide extension workers with the necessary information to effectively educate farmers on mitigating mycotoxin risks across various stages of grain handling and processing. By explaining these principles clearly, this guide simplifies the complexities of mycotoxin management for practical use in diverse agricultural contexts